Douglas L. Mann, M.D.: The Role of Innate Immunity in Cardiac Injury and Repair

This talk will review the studies that suggest that heart has intrinsic “hard-wired” repair systems that were designed to lead to repair and/or regeneration of cardiac tissue.

However, when this intrinsic repair system is excessively activated for a prolonged period of time, it can lead to adverse consequences, including dilation and dysfunction of the heart that lead, ultimately to the development of heart failure.